July 31, 2018
Posted in Uncategorized

The Frustrating Predicament of PPE Compliance

July 26, 2018 [Contagion Live] A recent study published in JAMA explores how Personal Protective Equipment use is often imperfectly executed. High PPE failure rates leave some experts pushing for better environmental cleaning and good hand hygiene. But rather than planning for failure, leaning into more robust PPE practices can make a huge difference in protecting patients and staff. Read more here

Very Empty (and Very Full) Hospitals Have Lowest C. Diff Risk

July 24th, 2018 [M Health Lab] The risk of C. diff infection was more than three times higher when the hospital was between 25 percent and 75 percent full, compared with less than 25 percent or more than 75 percent occupancy. Read full article here 

Microbiota-Based Enema Prevents Recurrent C. difficile Infections

July 20th, 2018 [MD Magazine] “Rebiotix is seeking FDA Biologics License Application (BLA) approval for a microbiota replacement product [RBX2660] that will be readily available to physicians and has been demonstrated to be both safe and effective in preventing further recurrence of CDI in patients who have already had multiple CDI episodes,” study author and presenter Dale Gerding, MD, of the Veterans Affairs Hospital in Hines, IL, told MD Magazine®. “Current ‘stool bank’ purchasing sites are not gathering sufficient data to meet these FDA requirements for safety and efficacy that are needed to assure physicians and patients. These safety and efficacy issues will be addressed through the FDA approval process.” Read more here 

Innovation Spotlight—Mount Sinai Health System Combats C. Difficile Infection

July 20th, 2018 [Hanys] In 2016, Mount Sinai Health System made reducing hospital-onset C. diff infection (HO-CDI), across all their sites, a top priority. “Between 2013 and 2016, these efforts reduced HO-CDI from 7.23 per 10,000 patient-days to 4.13 per 10,000 patient-days, a 43% reduction. Additionally, each hospital decreased its HO-CDI-rate by between 32% and 79%. Hand hygiene compliance also improved from 63% in 2015 to 81% in 2016.” Read more here

Study Fidaxomicin ‘better option’ than Vancomycin in many C. difficile Cases

July 19th, 2018 [Healio] “Based on a systematic review and network meta-analysis, researchers said fidaxomicin is a “better” option than vancomycin for the treatment of Clostridium difficile in all patients except those with severe infections and that metronidazole “should not be recommended,” to treat the infection.” Read more here 

Reducing Healthcare-Associated Infections Incidence by a Probiotic-Based Sanitation System: A Multicentre, Prospective, Intervention Study

July 12, 2018 [PLOS One] In multiple Italian studies, probiotic cleaners were shown to lower HAI rates, read more here

 

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