Read what leaders and experts are saying about Clostridium difficile infections (CDIs), the microbiome, antibiotic resistance, and the Peggy Lillis Foundation.

On Clostridium difficile Infections

“C. difficile infections cause immense suffering and death for thousands of Americans each year. These infections can be prevented by improving antibiotic prescribing and by improving infection control in the healthcare system.” – Tom Frieden, MD, MPH – Former Director of the Centers for Disease Control and Prevention (Source)

“Taking antibiotics is the most important risk factor for developing C. difficile infections. When a person takes antibiotics, beneficial bacteria that are normally present in the human gut and normally protect against infection can be altered or suppressed for several weeks to months.” – Clifford McDonald, MD – Senior Advisor for Science and Integrity of CDC’s Division of Healthcare Quality Promotion (Source)

“The numbers are pretty striking. A substantial number of [C. diff] cases are occurring in people who have never been to a hospital.” – Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases (Source)

“We found that CDI readmissions for any reason had almost a one week longer average length of stay than all-cause readmissions. This suggests that CDI readmissions place a burden on the health system by requiring patients to stay in the hospital longer, leading to less patient bed turnover, and higher hospital costs.” – Dr. Teena Chopra, MPH, leading CDI expert from Detroit Medical Center’s Division of Infectious Diseases (Source)

C. diff continues to be a significant threat to the health, and sometimes lives, of hospitalized patients. Without undertaking proper prevention measures, C. diff could continue to grow into a major public health issue.” – Dr. Kamo Sidhwa, infectious disease specialist (Source)

 

On Fecal Microbiota Transplants

“Shit is a great drug.” – Dr. Bruce Hirsch, infectious disease specialist with North Shore LIJ Health Systems (Source)

“Think about your good bacteria being like a healthy lawn. When your lawn is healthy, you may get a dandelion or two but they can’t take over. But if you have something happen like a drought…doing a fecal transplant is like sodding a new lawn. You can lay down healthy bacteria.” – Dr. Colleen Kelly, gastroenterologist with the Women’s Medicine Collaborative (Source)

 

On Antibiotic Resistance

“You’ve got to protect human health beyond everything, and so we think eliminating shared-use antibiotics is the right way to go” – Craig Wilson, Vice President of Food Safety at Costco (Source)

“If antibiotic resistance were allowed to grow unchecked…the number of deaths per year would balloon to 10 million by 2050. For comparison, that is more than the 8.2 million per year who currently die of cancer and 1.5 million who die of diabetes, combined.” – Mary McKenna reporting on the Review on Antimicrobial Resistance’s 2014 paper (Source)

“There are two main things that need to be improved. Number one is how antibiotics are being used. Making sure that we use them when they’re truly necessary and only for as long as necessary. The second element is to ensure rigorous infection control in all health care settings. C-difficile infections must be diagnosed quickly and correctly.” – Michael Bell, Deputy Director of CDC’s Division of Healthcare Quality Promotion (Source)

“Imagine a world where Neosporin can’t keep your child’s scrapes safe from infection; strep throat has transformed from a nuisance to a fatal disease; pulling your teenager’s wisdom teeth, replacing your mother’s hip, managing your uncle’s chemotherapy, and your Cesarean section are now procedures deemed too risky to perform. This is a world absent of modern medicine, and it is in our future…We now have bacterial infections that only a few years ago could be cured and are now not responsive to any known antibiotics.” – Congresswoman Louise Slaughter, D-NY (Source)

“Antibiotic resistance is rising for many different pathogens that are threats to health. If we don’t act now, our medicine cabinet will be empty and we won’t have the antibiotics we need to save lives.” – Tom Frieden, MD, MPH – Former CDC Director (Source)

“Every time antibiotics are used in any setting, bacteria evolve by developing resistance. This process can happen with alarming speed. These drugs are a precious, limited resource—the more we use antibiotics today, the less likely we are to have effective antibiotics tomorrow.” – Steve Solomon, MD, Director of CDC’s Office of Antimicrobial Resistance (Source)

“It would be unforgivable if the great progress made in combating infectious diseases could be threatened by the lack of new drugs that are within reach, or for lack of common sense investment in infrastructure that keeps us safe from avoidable infections.” – The Review on Antimicrobial Resistance, Chaired by Jim O’Neill (Source)